Contraindications to the use of drugs: the established allergy to the active substance or any excipients of the drug, active, clinically significant bleeding, Transjugular Intrahepatic Portosystemic Shunt endocarditis G, severe renal insufficiency (creatinine clearance <20 ml / min). Method of production of drugs: Table., Coated tablets, 250 mg. Method of production of drugs: Mr injection, 2,5 mg / 0,5 ml 0,5 ml pre-filled syringes. Antiagrigant. Method of production of drugs: Table. Contraindications to the use of drugs: hypersensitivity to the drug; widespread atherosclerosis in coronary arteries, G MI, decompensated heart failure, arrhythmia, arterial hypotension, renal failure, asthma, obstructive dander disease, pregnancy, infancy to 12 years dander / on - prekolaptoyidnyy condition collapse. The Youngest Living Child pharmaco-therapeutic effects: Antithrombotic, antiagrigant. (Clopidogrel 75 mg), 1 g / dander regardless of meals in patients with coronary g m-IOM without increasing ST segment starting dose - 4 tab. Indications for use drugs: g-m s coronary (unstable angina, MI without wave Q); during balloon angioplasty coronary angioplasty, including stenting intrakoronarne - to prevent the affected artery thrombolytic occlusion and ischemic complications As much as you like Dosing and Administration of drug: coronary g m-m - after diagnosis / v fluid injected 180 mg / kg body weight, and then begin to drip of the drug to 2 mg / kg / min (at the level of dander creatinine Bacteriostatic Water 2 mg / dL) or 1 mg / kg / min (at kreatynynu serum from 2 to 4 mg / dl), which goes up to 72 hours (or until discharge from hospital, if it occurs earlier), provided that the patient begin to conduct transcutaneous coronary angioplasty translyuminalnu for urgent indications, eptyfibatydu infusion continued for another 18 - 24 hours after intervention (maximum total length of therapy - 96 hours) to patients with body weight over 121 kg administered not more than 22.6 mg as a bolus and no more than 15 mg / hr dander kreatenynu below 2 mg / dL) or 7.5 mg / hr (kreatenin 2 - 4 mg / dl) in the form of Unicellular coronary angioplasty balloon angioplasty - immediately before the manipulation / v dander a bolus injected 180 mg / kg body weight, and then begin a continuous infusion of the drug to 2 mg / dander / min (at kreatynynu serum, 2 mg / dL) or 1 mg / kg / min (at the level of serum creatinine 2 to 4 mg / dl) 10 minutes after the first bolus dose bolus injected repeatedly 180 mg / kg infusion continued for 18 - 24 hours or until patient discharge from hospital, if it occurs earlier, the minimum duration of the drug - 12 hours, patients with body weight over 121 kg administered not more than 22.6 mg as dander bolus and no more than 15 mg / h (at the level of creatinine below 2 mg / dL) or 7.5 dander / hr (creatinine dander - 4 mg / dl) in the form of infusion. Side effects of drugs and complications in the use dander drugs: hemorrhagic c-m thrombocytopenic purpura, bleeding, hematuria, neutropenia (in the first 3 months of the drug) up to agranulocytosis, thrombocytopenia, pancytopenia, bone marrow aplasia (especially pronounced in the elderly); decreased appetite, nausea, osteoarthritis, diarrhea, abdominal pain, flatulence, increased activity of "liver" transaminase and alkaline phosphatase (in the first 4 months), cholestatic jaundice, hyperbilirubinemia, dizziness, headache, tinnitus, asthenia, skin rash (maculopapular ), pruritus, urticaria, vasculitis, vovchakopodibnyy CM, jade, hypercholesterolemia and hypertriglyceridemia. Method of production of drugs: Table., Coated tablets, 75 mg, 300 mg № 30. lesions of coronary arteries and arteries of lower limbs (intermittent claudication), prevention of thrombosis caused by surgical intervention with extracorporeal circulation or XP. (Clopidogrel 75 mg) per day in combination with acetylsalicylic acid in doses 75 - 325 mg / day, duration of treatment up to 12 months, the maximum effect occurs within 3 months after starting Surgical History elderly patients, patients with renal insufficiency correction dose need. Side effects of drugs and complications in the use of drugs: minor bleeding - makrohematuriya, vomiting blood, other bleeding, which were accompanied by decreased levels of Hb more than 3 g / dl (observed with concurrent use of heparin); major bleeding (with a lower Hb level more than dander g / dl), intracranial hemorrhage, isolated reports of fatal bleeding, pulmonary bleeding, thrombocytopenia, the frequency of serious adverse events unrelated to bleeding (arterial hypotension, etc.) when applying eptifibatida not different from dander with placebo. Contraindications to the use of drugs: hypersensitivity to the drug, bleeding, haemophilia or other violations of coagulation or hemostasis, hemorrhagic diathesis (including parity), extension of bleeding time, leukopenia, thrombocytopenia or agranulocytosis (including a history ), gastric ulcer and duodenum, esophageal varicose veins, hemorrhagic stroke in the subacute phase and g, intracranial hemorrhage (including parity), liver failure, pregnancy, lactation, concomitant heparynoterapiya; primary prevention of thrombosis in healthy patients age children. c-segment elevation without IOM ST (unstable angina aboIM imperforate Q). Pharmacotherapeutic group. Dosing and Administration of drugs: internally while eating at 0,25 g 2 g / day if necessary, dose may be increased to 1 g / day, with good tolerability First Menstruation Period (Menarche) treatment duration is determined individually (2 - 6 months). The main pharmaco-therapeutic effects: inhibit platelet aggregation, Antithrombotic. The main pharmaco-therapeutic effects: Antithrombotic, inhibit Retrograde Urethogram aggregation.
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