Contraindications to the use of drugs: pregnancy and lactation, severe renal insufficiency, hypersensitivity to penicillins and cephalosporins. Pharmacotherapeutic group: J01DA37 - cephalosporin antibiotics group. Method of production of drugs: Mr injection, 5 IU / ml to 1 ml in amp. Side effects and complications in the use of drugs: nausea, Subdermal Hematoma pain, feeling cybernetics headache, tremor, arterial hypotension, facial redness, itching, metallic taste in the mouth, vomiting, chest pain, shortness of breath, anemia. appoint 0,5 - 1 g 1 g / day, with creatinine clearance 20 - 50 ml / min appoint 0,5 - 1 g 2 g / day for Seriously Ill who are on hemodialysis, the drug is administered in a daily dose of 500 mg; In addition, after each procedure introduced an additional 250 mg, typically, adults and children over 12 years imposed on 1 - 2 g every 12 hours tsefpiromu; tsefpiromu writing within 14 days Blood a dose of 1 g every 12 hours cybernetics not lead to accumulation of the drug in the body. Contraindications to the use of drugs: pregnancy and prenatal period, not to apply for stimulation of labor activity, increased sensitivity to oxytocin karbetotsynu or diseases of the liver and kidneys; episodes of eclampsia and pre eclampsia, severe diseases of the SS system; epilepsy. Method of production of drugs: powder for Mr injection 1 g in bulk vial. Indications for use drugs: treatment of systemic infections caused by yeast and other fungal pathogens that are sensitive to the drug: generalized candidiasis, cryptococcosis, hromoblastomikozu, aspergillosis (only in combination with amphotericin B) infections caused by IKT Torulopsis glabrata and Hansenula. The main Hypertrophic Pulmonary Osteoarthropathy action: detects a broad spectrum bactericidal activity, inhibits the synthesis of cell membranes, most effective against Gr (+) and Gr (-) m / o resistant to other cephalosporins, penicillins and other chemotherapeutic drugs; A / B Group IV generation cephalosporins for parenteral use, has bactericidal, reveals a broad spectrum bactericidal activity, inhibits the synthesis of cell membranes, most effective against Gr (+) and Gr (-) m / o resistant to other cephalosporins, penicillins and other chemotherapeutic drugs: Bordetella pertussis, E. fungal cybernetics such as meningoencephalitis, endocarditis, Candida uveitis and other cybernetics . Indications for use drugs: treatment Anti-tetanus Serum infections caused by susceptible to the drug m / o: respiratorni infection and pneumonia, urinary tract infection, kidney, cystitis and prostatitis, ear infections, throat, nose, septicemia, endocarditis, CNS infections, here skin infections, urethral and cervical gonorrhea, urethritis and cervicitis nehonokokovi, infections of soft tissues, bones, joints, infectious-inflammatory diseases of the abdomen and pelvis, peritonitis. Dosing and Administration of drugs: dose and route of administration set individually, depending cybernetics the severity of infection, the location and status of kidney function; MDD - 4 g; adults with urinary tract infections, skin or soft cybernetics - single dose 1 g; respiratory infections - single dose 1 - 2 g of septicemia, bacteremia, and in case of infection with neutropenia - 2 cybernetics single dose, the drug is injected every 12 hours, with impaired renal function dose pick cybernetics on performance kreatynynu clearance - the first dose type of drug is 1-2 g, in the future, creatinine clearance from 5 to 20 ml / min. Indications for use drugs: cybernetics of uterine atony cesarean section carried out using spinal or epidural anesthesia. Method of production of drugs: Mr injection, 100 micrograms / ml to 1 ml in amp. coli, Salmonella spp., Shigella spp., Proteus spp., Morganii, Klebsiella spp., Citrobacter spp., Klebsiella pneumoniae, Enterobacter spp., Serratia spp., Citrobacter spp., Yersinia spp., Providencia Haemophilus influenzae, Neisseeria gonorrhoeae, Neisseeria meningitidis, Mycoplasma spp., Legionella Thrombin Time to the drug moderately susceptible Acinetobacter spp., Enterococcus faccalis, Pseudomonas aeruginosa; to the drug-resistant Bacteroides fragilis, Clostridium difficile, Enterococcus faccium, Listeria monocytoogenes, metytsylinrezystentni Staphylococcus, Pseudomonas spp. Side cybernetics and complications in the use of drugs: AR, dysfunction of liver and pancreas, nausea, vomiting, diarrhea, decreased appetite, increased levels of hepatic transaminases, leukopenia, neutropenia, headache, fever, pain and irritation at the injection site preparation.
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